al 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T29809	AL-1	AL 1,AL1
	AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variet...
T9506	Trans,trans-2,4-Decadienal	trans,trans-2,4-Decadien-1-al	Others
	trans,trans-2,4-Decadienal (trans,trans-2,4-Decadien-1-al) is a product found in Antiaris toxicaria.		Others
T21224	(+)-Fluprostenol	Fluprostenol, (+)-,Travoprost acid,AL-5848	Prostaglandin Receptor
	(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).		Prostaglandin Receptor
T2514	Linifanib	ABT-869,RG3635,AL-39324	Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
	Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T12628	(R)-MG-132	(S,R,S)-(-)-MG-132,Z-Leu-D-leu-leu-al	Proteasome
	(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.		Proteasome
T31305	Decanal, 2-ethylidene-	2-Ethylidenedecan-1-al
	Decanal, 2-ethylidene- is a biochemical.
T31306	Decanal, 2-methylene-	2-Methylenedecanal,EINECS 244-979-4,2-Methylenedecan-1-al
	Decanal, 2-methylene- is a biochemical.
T20984	Lumogallion	4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid	Others
	Lumogallion (4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid) is an azo reagent used in the determination of metal ions, such as the research of V, Fe, and Al.		Others
T37807	JTV 519 fumarate
	Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo. Hunt et al (2007) K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]r...
T37345	5,7-Dihydroxycoumarin		Antibacterial
	5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescences of Macaranga triloba. 5,7-Dihydroxycoumarin has antibacterial activities[1][2]. [1]. Ishak Zakaria, et al. Flavonoids with antiplasmodial and cytotoxic...		Antibacterial
T35610	2,5-dimethyl Celecoxib		Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor
	2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 μM) and reduces prostaglandin ...		Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor
T36520	COR659		Cannabinoid Receptor , GABA Receptor
	COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effects via a composite mechanism, including positive allosteri...		Cannabinoid Receptor , GABA Receptor
T36949	Niaprazine		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
	Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff...		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
T37886	1-Heptadecanol		Antibacterial
	1-Heptadecanol is a long-chain primary alcohol with antibacterial activity from Solena amplexicaulis leaves[1]. [1]. Soumendranath Chatterjee, et al. Antibacterial Activity of Long-Chain Primary Alcohols from Solena ampl...		Antibacterial
T36648	Tucatinib hemiethanolate
	Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-f...
T37709	2,2,2-Trichloroethanol		Potassium Channel , Endogenous Metabolite
	2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...		Potassium Channel , Endogenous Metabolite
T37197	5-HT1A modulator 2 hydrochloride		5-HT Receptor
	5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT , is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1]. [1]. Naiman, N.,et al. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotoni...		5-HT Receptor
T38240	2,6-Dichlorodiphenylamine		Antibacterial
	2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...		Antibacterial
T36083	DS-7423		PI3K , mTOR
	DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2]. DS-7423 increases TP53 expression, the level of p-TP53 on Ser...		PI3K , mTOR
T37734	AMPA receptor modulator-2		GluR
	AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AM...		GluR